One Night Stand (2008) was a pay-per-view event produced by World Wrestling Entertainment (WWE) that took place on June 1, 2008, at the San Diego Sports Arena in San Diego, California. It was the fourth and final event promoted under the WWE One Night Stand name. The event featured talent from the Raw, SmackDown, and ECW brands.
- Dark - Matt Hardy defeated Shelton Benjamin
- Jeff Hardy defeated Umaga - Falls Count Anywhere match
- Big Show defeated CM Punk, John Morrison, Tommy Dreamer, and Chavo Guerrero - Singapore Cane match for an ECW Championship match at WWE Night of Champions 2008
- John Cena defeated John Bradshaw Layfield - First Blood match
- Beth Phoenix defeated Melina - "I Quit" match
- Batista defeated Shawn Michaels - Stretcher match
- Triple H (c) defeated Randy Orton - Last Man Standing match for the WWE Championship
- Edge defeated The Undertaker - Tables, Ladders, and Chairs match for the vacant WWE World Heavyweight Championship; since The Undertaker lost, he was forced to leave WWE.