Extreme Rules (2010) was a pay-per-view event produced by World Wrestling Entertainment (WWE) and presented by KFC, which took place on April 25, 2010, at the 1st Mariner Arena in Baltimore, Maryland. It was the second event promoted under the WWE Extreme Rules name. There were eight matches scheduled on the event's card, all of which featured an extreme stipulation, with no regular singles matches on the card. The event received 182,000 pay-per-view buys, the same as the figure achieved WWE Backlash 2009.
- DARK - Kofi Kingston defeated Dolph Ziggler
- The Hart Dynasty (David Hart Smith and Tyson Kidd) (with Natalya and Bret Hart) defeated ShoMiz (Big Show and The Miz), John Morrison and R-Truth, and The World's Strongest Tag Team (Montel Vontavious Porter and Mark Henry)[ Gauntlet match; since ShoMiz lost, the winning team earned a future Unified WWE Tag Team Championship match
- CM Punk (with Luke Gallows and Serena) defeated Rey Mysterio - Hair match: had Punk lost, his head would have been shaved by Mysterio.
- JTG defeated Shad Gaspard - Strap match
- Jack Swagger (c) defeated Randy Orton - Extreme Rules match for the WWE World Heavyweight Championship
- Sheamus defeated Triple H - Street Fight
- Beth Phoenix defeated Michelle McCool (c) (with Vickie Guerrero and Layla) - Extreme Makeover match for the WWE Women's Championship
- Edge defeated Chris Jericho - Steel cage match
- John Cena (c) defeated Batista - Last Man Standing match for the WWE Championship