Piper headlined several major pay-per-view events; he participated in the main events of WWE WrestleMania 1 and WWE WrestleMania 10, as a special guest referee in the latter. He accumulated 34 championships in various promotions during his career. Piper's most notable rivals included Greg Valentine, Adrian Adonis, and Hulk Hogan, with the feud against Hogan also involving Captain Lou Albano and singer Cyndi Lauper, considered the beginning of Rock N' Wrestling. Piper was inducted into the WWE Hall of Fame in 2005 and named as the top villain in wrestling history by WWE. Piper acted in dozens of films and TV shows, including the lead role in 1988's They Live and a recurring role in It's Always Sunny in Philadelphia.
On July 31, 2015, Piper died in his sleep after a heart attack, at the age of 61, in his home in Hollywood, California. Piper is survived by his wife, Kitty, their four children and four grandchildren. News of his death broke minutes before the Hall of Heroes dinner to cap off the Mid-Atlantic Wrestling Legends FanFest in Charlotte, North Carolina, where about 600 current and former wrestling personalities and fans had gathered. He received a ten-bell salute after the planned salute to fellow former professional wrestler and WWE Hall of Famer Dusty Rhodes, who had died in June 2015.
Vince McMahon, the CEO of WWE, also made a statement, commenting that: "Roddy Piper was one of the most entertaining, controversial and bombastic performers ever in WWE, beloved by millions of fans around the world. I extend my deepest condolences to his family". Hollywood director John Carpenter also said: "Devastated to hear the news of my friend Roddy Piper’s passing today. He was a great wrestler, a masterful entertainer and a good friend."
In an HBO Real Sports interview conducted by Piper in 2003, he had predicted that he was "not going to make 65" due to his poor lifestyle, and that his 2003 return to WWE was because he could not access his pension fund until reaching the age of 65.
- National Wrestling Alliance Mid-Atlantic Heavyweight Championship
- National Wrestling Alliance Mid-Atlantic Tag Team Championship
- National Wrestling Alliance Television Championship
- WCW United States Heavyweight Championship
- National Wrestling Alliance Canadian Tag Team Championship (Vancouver version)
- National Wrestling Alliance Americas Heavyweight Championship
- National Wrestling Alliance Americas Tag Team Championship
- National Wrestling Alliance World Light Heavyweight Championship
- National Wrestling Alliance United States Heavyweight Championship (San Francisco version)
- National Wrestling Alliance World Tag Team Championship (San Francisco version)
- National Wrestling Alliance Pacific Northwest Heavyweight Championship
- National Wrestling Alliance Pacific Northwest Tag Team Championship
- National Wrestling Alliance American Tag Team Championship
- WWE World Tag Team Championship
- WWE Intercontinental Championship