Bound for Glory (2006) was a pay-per-view (PPV) event produced by Total Nonstop Action Wrestling, which took place on October 22, 2006 from the Compuware Sports Arena in the Detroit, Michigan charter township of Plymouth. Tickets went on sale August 5, 2006. It was the second event under the TNA Bound for Glory chronology. Eight professional wrestling matches were featured on the event's card, with Jeff Jarrett defending his NWA World Heavyweight Championship against Sting with the stipulation that Sting would retire from professional wrestling if he'd lose.
Bound for Glory was the first TNA pay-per-view event held in a location other than Nashville, Tennessee, or Orlando, Florida, since the first two weekly pay-per-views in June 2002, which were held in Huntsville, Alabama. The Compuware Sports Arena was also the site of the first TNA house show. This was the first pay-per-view to feature a half-hour "Road to" preview airing the night before. This continued for future pay-per-views. This was the first and only time that all of TNA's active championships at the time changed hands in one night.
- Bobby Roode (with Traci Brooks) defeated Lance Hoyt
- Austin Starr last eliminated Jay Lethal to win - Kevin Nash Open Invitational X Division Gauntlet battle royal
- Team 3D (Brother Ray and Brother Devon) defeated America's Most Wanted (Chris Harris and James Storm), The James Gang (B.G. James and Kip James), and The Naturals (Chase Stevens and Andy Douglas)
- Samoa Joe defeated Abyss (with James Mitchell), Brother Runt and Raven - Monster's Ball match with Jake Roberts as the special guest referee
- Eric Young defeated Larry Zbyszko - Loser Gets Fired match
- Chris Sabin defeated Senshi (c) for the TNA X Division Championship
- Christian Cage defeated Rhino - 8 Mile Street Fight
- The Latin American Xchange (Homicide and Hernandez) (with Konnan) defeated A.J. Styles and Christopher Daniels (c) Six Sides of Steel match for the NWA World Tag Team Championship
- Sting defeated Jeff Jarrett (c) - Title vs. Career match for the NWA World Heavyweight Championship with Kurt Angle as the special outside enforcer