As a singles wrestler, he is a one-time World Champion having held the ECW Championship once in 2008, and a six-time WCW/WWE Cruiserweight Champion.
He has also achieved notable success in tag team wrestling, being a five-time World Tag Team Champion - winning the WWE Tag Team Championship twice with Eddie Guerrero as Los Guerreros, the WCW World Tag Team Championship with Corporal Cajun once as the Misfits in Action, and the TNA World Tag Team Championship with Hernandez twice. Between WCW, WWE, and TNA, Guerrero has held a dozen total championships.
He is the grandson of Gory Guerrero; the son of Chavo Guerrero Sr.; the nephew of Eddie Guerrero, Hector Guerrero, and Mando Guerrero; the great-nephew of Enrique Llanes; and the cousin of Javier Llanes, Hector Mejia and Shaul Guerrero. His grandfather, Gory Guerrero, was one of the most famous wrestlers in Mexican history. His father, Chavo Guerrero Sr., was also a legendary wrestler in Mexico and worked in WWE as a manager and part-time wrestler. One of his uncles, Eddie Guerrero, was a former WWE Champion and a Hall of Famer. Chavo Jr. has two other uncles (Mando and Hector) who have had successful careers in the business.
- Ring Ka King Tag Team Championship
- TNA World Tag Team Championship
- Vendetta Pro Wrestling Heavyweight Championship
- WWE/WCW Cruiserweight Championship
- WCW World Tag Team Championship
- World Wrestling Council Caribbean Heavyweight Championship
- ECW Championship
- WWE Tag Team Championship